1,2-Ethanediamine, N1,N1,N2-trimethyl- → N-[4-(4-{2-[bis-(4-methoxy-benzyl)-amino]-pyrimidin-5-yl}-2-morpholin-4-yl-5,6-dihydro-pyrrolo[2,3-d]pyrimidin-7-yl)-pyridin-2-yl]-N,N',N'-trimethyl-ethane-1,2-diamine

HRID 138471Notes

Reaction equation

HRID 138471 reaction equation
[CH3:48][N:49]([CH2:50][CH2:51][NH:52][CH3:53])[CH3:54].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([N:8]2[CH2:9][CH2:10][c:11]3[c:12]2[n:13][c:14]([N:42]2[CH2:43][CH2:44][O:45][CH2:46][CH2:47]2)[n:15][c:16]3-[c:17]2[cH:18][n:19][c:20]([N:23]([CH2:24][c:25]3[cH:26][cH:27][c:28]([O:31][CH3:32])[cH:29][cH:30]3)[CH2:33][c:34]3[cH:35][cH:36][c:37]([O:40][CH3:41])[cH:38][cH:39]3)[n:21][cH:22]2)[cH:7]1>>[c:2]1([N:52]([CH2:51][CH2:50][N:49]([CH3:48])[CH3:54])[CH3:53])[n:3][cH:4][cH:5][c:6]([N:8]2[CH2:9][CH2:10][c:11]3[c:12]2[n:13][c:14]([N:42]2[CH2:43][CH2:44][O:45][CH2:46][CH2:47]2)[n:15][c:16]3-[c:17]2[cH:18][n:19][c:20]([N:23]([CH2:24][c:25]3[cH:26][cH:27][c:28]([O:31][CH3:32])[cH:29][cH:30]3)[CH2:33][c:34]3[cH:35][cH:36][c:37]([O:40][CH3:41])[cH:38][cH:39]3)[n:21][cH:22]2)[cH:7]1

Participants

3

Reactant 2

HCID 673381,2-Ethanediamine, N1,N1,N2-trimethyl-HCID 45258863HCID 45258863, compound

Product 1

HCID 67385250N-[4-(4-{2-[bis-(4-methoxy-benzyl)-amino]-pyrimidin-5-yl}-2-morpholin-4-yl-5,6-dihydro-pyrrolo[2,3-d]pyrimidin-7-yl)-pyridin-2-yl]-N,N',N'-trimethyl-ethane-1,2-diamine

Sources & evidence

ORD record
ord-ea243e993cb44193909b79760473a606
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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