HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 138472Generated: October 30, 2026
Dichloromethane → 6-[(3-{[Tert-butyl(dimethyl)silyl]oxy}propyl)amino]-2-chloro-5-fluoronicotinonitrile
https://huagongshe.com/reaction/138472
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Reactant | tert-Butyldimethylsilyl chloride | HCID 28928 | — |
| Reactant | 2,6-Dichloro-5-fluoro-3-pyridinecarbonitrile | HCID 2733849 | — |
| Reactant | 2-Chloro-5-fluoro-6-[(3-hydroxypropyl)amino]nicotinonitrile | HCID 86604598 | — |
| Product | 6-[(3-{[Tert-butyl(dimethyl)silyl]oxy}propyl)amino]-2-chloro-5-fluoronicotinonitrile | HCID 86604597 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (9/10) |
|---|
| ORD ID | ord-a83cfcff49d04047a72afc1cd3539a4c |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (9/10) |
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