HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → Ethyl 6-chloro-1-methyl-1H-indole-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Ethyl 6-chloroindole-2-carboxylate | HCID 7015027 | — |
| Product | Ethyl 6-chloro-1-methyl-1H-indole-2-carboxylate | HCID 10561874 | — |
Reaction Steps
The preparation is carried out as in Example 1.1, from 8.0 g (35.8 mmol) of ethyl 6-chloro-1H-indole-2-carboxylate, from 1.8 g of 60% sodium hydride and from 2.8 ml of iodomethane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06262045B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-be5e25e27a6846618217e2d7563ceecf |
| Source note | uspto-grants-2001_07 |