Potassium Hydroxide → HCID 23696302, compound
Reaction equation
[OH-].[K+:2].[S:3]1[C:7]([C:8]([O:10]CC)=[O:9])=[CH:6][N:5]=[N:4]1>O.C(O)C>[S:3]1[C:7]([C:8]([O-:10])=[O:9])=[CH:6][N:5]=[N:4]1.[K+:2]Participants
5
Reactant 2
Product 1
Reagents, catalysts & solvents 2
Conditions
- Temperature
- 23 °C
Procedure
A solution of potassium hydroxide (3.30 g.) in water (7 ml.) was added to a solution of ethyl 1,2,3-thiadiazole-5-carboxylate (8.00 g.) in ethanol (25 ml.). The mixture was stirred at 23° C. for 2 hours, and then was worked up to yield potassium 1,2,3-thiadiazole-5-carboxylate. A suspension of this salt (3.00 g.) in toluene (25 ml.) was treated at 0° C. with oxalyl chloride (1.6 ml.), stirred at 0° C. for 1 hour, and then was worked up to yield 1,2,3-thiadiazole-5-carbonyl chloride.
Sources & evidence
- ORD record
- ord-0d97ecc5112e4513be54f3d9d3f9d958
- Source dataset
- uspto-grants-2001_07
- Patent number
- US06262059B1
Reaction notes
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