HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl nipecotate → Ethyl (S)-3-Piperidinecarboxylate D-Tartrate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl nipecotate | HCID 98969 | — |
| Reactant | D-Tartaric acid | HCID 439655 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl (S)-3-Piperidinecarboxylate D-Tartrate | HCID 14183617 | — |
Reaction Steps
Ethyl 3-piperidinecarboxylate (200 g) was combined with (-)-D-tartaric acid (191 g) in hot 95% ethanol. The resulting precipitate was filtered and recrystallized six times from 95% ethanol to give (S)-ethyl 3-piperidinecarboxylate D-tartrate salt of high optical purity as determined by chiral HPLC analysis.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06262078B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-c8a859e7772840178991237cb6680339 |
| Source note | uspto-grants-2001_07 |