HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 70238480, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 54284623 | HCID 54284623 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 70238480 | HCID 70238480 | 66% |
Reaction Steps
The (S)-1-cyclopropylmethyl-3-(2,6-dimethylphenoxymethyl)piperidine was dissolved in dry ether (125 mL) and treated with 1M hydrochloric acid in ether (18.9 mL). The white precipitate was collected and dried under vacuum to give (S)-1-cyclopropylmethyl-3-(2,6-dimethylphenoxymethyl)piperidine hydrochloride, (3.6 g, 66%), m.p. 137.3-137.5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06262078B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-46ce9f24568349999b28d56df9addd31 |
| Source note | uspto-grants-2001_07 |