HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isobutylbenzene → Ethyl 4-iso-butylbenzoylformate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isobutylbenzene | HCID 10870 | — |
| Reactant | Ethyl 4-phenylbenzoylformate | HCID 80389 | — |
| Product | Ethyl 4-iso-butylbenzoylformate | HCID 12585534 | 81% |
Reaction Steps
A mixture of 27 g (200 mmol) of isobutylbenzene and 24 mL (215 mmol) of ethyl oxalylchloride underwent Friedel-Crafts acylation reaction in an analogous fashion as described for the synthesis of ethyl 4-phenylbenzoylformate to yield 38 g (81% yield) of ethyl 4-isobutylbenzoylformate as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06262073B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-3cdb522f25f4440fb7b270295dc8584f |
| Source note | uspto-grants-2001_07 |