反应详情

0.1 mol of 8-methylquinoline-5-carboxylic acid was suspended in 1.5 l of ethanol and admixed with 10.0 g of palladium on activated carbon (5%). Over a period of 48 hours, the mixture was reduced in an autoclave at 50° C. using hydrogen (1 bar) (HPLC control). The reaction mixture was then filtered, the filter cake was washed with ethanol and the combined organic filtrates were concentrated.

1. customwas reduced in an autoclave at 50° C.
2. filtrationThe reaction mixture was then filtered
3. washthe filter cake was washed with ethanol
4. concentrationthe combined organic filtrates were concentrated