Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | 1,3-Dihydroindene-2,2-dicarboxylic acid | HCID 251957 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | 2-Indancarboxylic Acid | HCID 575777 | 35.1% |
Reaction Steps
A solution of indane-2,2-dicarboxylic acid (17 g, Baeyer and Perkin, Ber. 1884, 17, 122) in NMP (200 ml) was heated to 150° C. for 1 hour. After cooling to 20° C. the solution was poured in water (300 ml) and concentrated hydrochloric acid was added to pH=1. Conventional work up with ether gave the title product (4.7 g). Mp 132-33° C. (from ether).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06262087B1 |
|---|
| Source dataset | uspto-grants-2001_07 |
|---|
| ORD ID | ord-3ca22b31d0584613a61ea44396cdfdf6 |
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| Source note | uspto-grants-2001_07 |
|---|
