1-[4-[(6-Bromohexyl)oxy]butyl]benzene → HCID 70084117, compound

HRID 1385109Notes

Reaction equation

HRID 1385109 reaction equation
[CH3:1][O:2][C:3]([C:5]1[CH:13]=[C:12]2[C:8]([C:9]([CH2:14][CH3:15])=[N:10][NH:11]2)=[CH:7][CH:6]=1)=[O:4].[C:16]1([CH2:22][CH2:23][CH2:24][CH2:25][O:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32]Br)[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[CH3:1][O:2][C:3]([C:5]1[CH:13]=[C:12]2[C:8]([C:9]([CH2:14][CH3:15])=[N:10][N:11]2[CH2:32][CH2:31][CH2:30][CH2:29][CH2:28][CH2:27][O:26][CH2:25][CH2:24][CH2:23][CH2:22][C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=2)=[CH:7][CH:6]=1)=[O:4]

Participants

3

Reactant 2

HCID 110124391-[4-[(6-Bromohexyl)oxy]butyl]benzeneHCID 178438014HCID 178438014, compound

Product 1

HCID 70084117HCID 70084117, compoundYield 56%

Procedure

This compound was prepared according to the method of Preparation 3, using 137 mg (0.671 mmol, 1.0 equiv) 3-ethyl-1H-indazole-6-carboxylic acid methyl ester and 273 mg (0.872 mmol, 1.3 equiv) 6-(4-phenyl-butoxy)-hexyl bromide as starting materials to give 163 mg (56%) of a yellow oil: HRMS calcd for C27H36N2O3+H: 437.2804. Found 437.2833.

Workup

  1. customThis compound was prepared
  2. customaccording to the method of Preparation 3

Sources & evidence

ORD record
ord-bdc9fd3f44b746c4906fbd4433ede4e9
Source dataset
uspto-grants-2001_07
Patent number
US06262040B1

Reaction notes

Loading…