Bromoform → 39647-01-3

Participants

Reaction Steps

To a solution of methyl methacrylate (3.15 g, 31.6 mmol), benzyltriethylammonium chloride (TEBA) (0.72 g, 10 mol %), in 12.6 mL of 50% sodium hydroxide solution was added bromoform (15.95 g, 63 mmol). The reaction was stirred overnight and then extracted with dichloromethane (2×25 mL). The organic extracts were washed with brine, dried (MgSO4), and then condensed in vacuo. The residue was purified by bulb to bulb distillation to give 6.5 g of the known product as an oil. 1H NMR (CDCl3) δ3.8 (s, 3H), 2.4(d, 1H), 1.6 (s, 3H), 1.5 (d, 1H).

Provenance & Evidence