Sulfuric Acid → HCID 21184396, compound

HRID 1385208Notes

Reaction equation

HRID 1385208 reaction equation
[O:1]=[C:2]1[C:11]2[N:12]=[C:13]([C:15]3[CH:20]=[CH:19][N:18]=[CH:17][CH:16]=3)[S:14][C:10]=2[C:9](=[O:21])[C:8]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]1=2.[S:22](=[O:26])(=[O:25])([OH:24])[OH:23]>CO>[S:22]([OH:26])([OH:25])(=[O:24])=[O:23].[O:1]=[C:2]1[C:11]2[N:12]=[C:13]([C:15]3[CH:20]=[CH:19][N:18]=[CH:17][CH:16]=3)[S:14][C:10]=2[C:9](=[O:21])[C:8]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]1=2

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 14171304HCID 14171304, compound

Product 1

HCID 21184396HCID 21184396, compoundYield 75%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

To a suspension of 500 mg (1.71 mmol) of 4,9-dihydro-4,9-dioxo-2-(4-pyridyl)-naphtho[2,3-d]thiazole in 60 mL of methanol, 60 mL of a methanol solution containing 0.18 mL (1.74 mmol) of 98% sulfuric acid are added. After 1 h of reflux and complete cooling, the yellow precipitate obtained is filtered, rinsed several times with ethylic ether, and dried. In this manner, 500 mg of 4,9-dihydro-4,9-dioxo-2-(4-pyridyl)-naphtho[2,3-d]thiazole sulfate are obtained, in the form of yellow crystals.

Workup

  1. additionare added
  2. temperatureAfter 1 h of reflux
  3. customcomplete cooling, the yellow precipitate obtained
  4. filtrationis filtered
  5. washrinsed several times with ethylic ether
  6. customdried

Sources & evidence

ORD record
ord-961f7f501657488a86ca323bf88221ab
Source dataset
uspto-grants-2001_07
Patent number
US06262095B1

Reaction notes

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