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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1385273Generated: October 31, 2026

Dimethylformamide dimethyl acetal → Ethyl 3-(dimethylamino)-2-isocyanoacrylate

https://huagongshe.com/reaction/1385273

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamide dimethyl acetalHCID 78373—
ReactantEthyl isocyanoacetateHCID 533707—
SolventEthanolHCID 702—
ProductEthyl 3-(dimethylamino)-2-isocyanoacrylateHCID 54355309—

Reaction Steps

To a solution of ethyl isocyanoacetate (5.0 g) in ethanol (100 mL) is added N,N-dimethyl-formamide dimethyl acetal (6.5 g) dropwise with stirring over 10 minutes.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06262090B1
Source datasetuspto-grants-2001_07
ORD IDord-72f1b0c7ad5745329e439cb3a822e7d7
Source noteuspto-grants-2001_07