2,3-Difluoro-6-nitrophenol → 6-Amino-2,3-difluorophenol

Participants

Reaction Steps

2,3 difluoro 6-nitro phenol (2 g, 11 mmol) was treated with 10%Pd/C (1 g) at 23 ° C. The reaction mixture was flushed with hydrogen gas and the reaction was allowed to stir 12 h before it was filtered through celite. The filtrate was concentrated in vacuo to afforded the title compound (1.6 g, 97%). EI-MS m/z 146 (M+H)+

Provenance & Evidence