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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1385380Generated: October 30, 2026

(1,1'-Biphenyl)-3-ol, 4-nitro- → 2-Amino-5-phenylphenol

https://huagongshe.com/reaction/1385380

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-3-ol, 4-nitro-HCID 87437—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
Product2-Amino-5-phenylphenolHCID 20376—

Reaction Steps

A solution of 2-nitro 5-phenyl phenol (1.2 g, 5.5 mmol) in methanol was treated with 10% Pd/C (1.2 g). The reaction mixture was flushed with hydrogen and allowed to stir overnight. The reaction mixture was filtered through celite and the filtrate was concentrated in vacuo to afford desired (1.01 g, 98%). EI-MS m/z 186 (M+H)+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06262113B1
Source datasetuspto-grants-2001_07
ORD IDord-3b82b58ae9034a208443b76ab0f0a2c8
Source noteuspto-grants-2001_07