2-Amino-5-phenylphenol → HCID 22011350, compound

HRID 1385381Notes

Reaction equation

HRID 1385381 reaction equation
[OH:1][C:2]1[CH:8]=[C:7]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH:6]=[CH:5][C:3]=1[NH2:4].[Br:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[N:22]=[C:23]=[O:24]>>[OH:1][C:2]1[CH:8]=[C:7]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH:6]=[CH:5][C:3]=1[NH:4][C:23]([NH:22][C:17]1[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=1[Br:15])=[O:24]

Participants

3

Reactant 2

HCID 203762-Amino-5-phenylphenolHCID 1370972-Bromophenyl isocyanate

Product 1

HCID 22011350HCID 22011350, compound

Procedure

The urea was prepared from 2-hydroxy 4-phenyl aniline (O. 185 g, 1 mmol) and 2-bromo phenyl isocyanate (O. 198 g) by general Method B. It was purified by dilution of the DMF solution with methylene chloride and precipitation with hexane (215 mg, 56%). EI-MS m/z 383 (M+H)+

Workup

  1. customIt was purified by dilution of the DMF solution with methylene chloride and precipitation with hexane (215 mg, 56%)

Sources & evidence

ORD record
ord-d51b2ab4a09e4d45af80d32983b10cf8
Source dataset
uspto-grants-2001_07
Patent number
US06262113B1

Reaction notes

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