O-Phenylenediamine → 2-(Benzylsulfonylamino)aniline

HRID 1385393Notes

Reaction equation

HRID 1385393 reaction equation
[CH2:1]([S:8](Cl)(=[O:10])=[O:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:12]1([NH2:19])[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[NH2:18]>>[CH2:1]([S:8]([NH:18][C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=1[NH2:19])(=[O:10])=[O:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 7243O-PhenylenediamineHCID 74740Phenylmethanesulfonyl chloride

Product 1

HCID 167784432-(Benzylsulfonylamino)aniline

Procedure

The sulfonamide was synthesized from benzyl sulfonyl chloride (0.01 mol) and o-phenylene diamine (0.01 mol) by general Method C. It was purified by recrystallization from EtOH (0.87 g, 33%). EI-MS m/z 263 (M+H)+.

Workup

  1. customIt was purified by recrystallization from EtOH (0.87 g, 33%)

Sources & evidence

ORD record
ord-d6bc12f60e0b4283b1a45ed9d3a9679b
Source dataset
uspto-grants-2001_07
Patent number
US06262113B1

Reaction notes

Loading…