Dimedone → HCID 9927530, compound

HRID 1385500Notes

Reaction equation

HRID 1385500 reaction equation
[CH3:1][C:2]1([CH3:15])[CH2:13][C:12](=[O:14])[C:5]2[C:6]([C:9]([OH:11])=O)=[CH:7][O:8][C:4]=2[CH2:3]1.CC1(C)CC(=O)CC(=O)C1.[F:26][C:27]1[CH:33]=[C:32]([O:34][CH3:35])[CH:31]=[CH:30][C:28]=1[NH2:29]>>[F:26][C:27]1[CH:33]=[C:32]([O:34][CH3:35])[CH:31]=[CH:30][C:28]=1[NH:29][C:9]([C:6]1[C:5]2[C:12](=[O:14])[CH2:13][C:2]([CH3:1])([CH3:15])[CH2:3][C:4]=2[O:8][CH:7]=1)=[O:11]

Participants

4

Reactant 3

HCID 31358DimedoneHCID 7971096,6-Dimethyl-4-oxo-4,5,6,7-tetrahydro-benzofuran-3-carboxylic acidHCID 37563832-Fluoro-4-methoxyaniline

Product 1

HCID 9927530HCID 9927530, compound

Procedure

Starting with (6,6-dimethyl-4-oxo4,5,6,7-tetrahydro-benzofuran-3-carboxylic acid), prepared from dimedone by Procedure A, and 2-fluoro-4-methoxyaniline, General Procedure B provided the title compound as a white solid:

Sources & evidence

ORD record
ord-a990e1af7ac54927a7051da8fffbebf2
Source dataset
uspto-grants-2001_07
Patent number
US06262272B1

Reaction notes

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