Nonylamine → HCID 136364220, compound

HRID 1385541Notes

Reaction equation

HRID 1385541 reaction equation
Cl[C:2]1[N:3]=[C:4]([OH:19])[C:5]2[N:6]=[CH:7][N:8]([C:17]=2[N:18]=1)[C@@H:9]1[O:16][C@H:13]([CH2:14][OH:15])[C@@H:11]([OH:12])[CH2:10]1.[CH2:20]([NH2:29])[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28]>>[CH2:20]([NH:29][C:2]1[NH:3][C:4](=[O:19])[C:5]2[N:6]=[CH:7][N:8]([C:17]=2[N:18]=1)[C@@H:9]1[O:16][C@H:13]([CH2:14][OH:15])[C@@H:11]([OH:12])[CH2:10]1)[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28]

Participants

3

Reactant 2

HCID 16215NonylamineHCID 178521063HCID 178521063, compound

Product 1

HCID 136364220HCID 136364220, compound

Procedure

The compound 115 is prepared from compound 102 (9.5 g, 22 mmol) and nonylamine (9.58 g, 67 mmole) as per example 103. The crude product was evaporated to dryness and the residue was co-evaporated with a mixture of ethanol and toluene (three times). The resulting residue was dissolved in ethanol and cooled to yield a small amount of product. It was filtered and the filtrate evaporated to dryness. The residue was used without characterization.

Workup

  1. customThe crude product was evaporated to dryness
  2. additionthe residue was co-evaporated with a mixture of ethanol and toluene (three times)
  3. dissolutionThe resulting residue was dissolved in ethanol
  4. temperaturecooled
  5. customto yield a small amount of product
  6. filtrationIt was filtered
  7. customthe filtrate evaporated to dryness

Sources & evidence

ORD record
ord-71337cd97d9b4429a670560ba66e7d07
Source dataset
uspto-grants-2001_07
Patent number
US06262241B1

Reaction notes

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