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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1385678Generated: November 2, 2026

o-Tolylacetic acid → 2-[(2-methylphenyl)acetamido]butyric Acid Iso-butyl Ester

https://huagongshe.com/reaction/1385678

Reaction equation

Participants

RoleNameHCIDCharge
Reactanto-Tolylacetic acidHCID 69519—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(2-methylphenyl)acetamido]butyric Acid Iso-butyl EsterHCID 54573498—

Reaction Steps

Following General Procedure I′ above and using 2-methylphenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06262302B1
Source datasetuspto-grants-2001_07
ORD IDord-1447ba6afc8c42c398ee6fe0e16ac8e8
Source noteuspto-grants-2001_07