HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Cyclohexanedicarboxylic acid → HCID 53995729, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Cyclohexanedicarboxylic acid | HCID 107205 | — |
| Reactant | benzyl (2R)-pyrrolidine-2-carboxylate hydrochloride | HCID 22827650 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 53995729 | HCID 53995729 | 70% |
Reaction Steps
Using General Procedure A with 5.6 g (23.2 mmol) D-Proline benzyl ester hydrochloride and 2.0 g (11.6 mmol) cyclohexane-1,3-dicarboxylic acid afforded, after flash chromatography (EtOAc), 4.4 g (70%) of the title compound as a colorless oil. MS m/e (%): 547 (M+H+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06262089B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-936fa2de63d84b03b3bcbd9905395e48 |
| Source note | uspto-grants-2001_07 |