HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Phenylenediacetic acid → HCID 54405893, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Phenylenediacetic acid | HCID 29788 | — |
| Reactant | benzyl (2R)-pyrrolidine-2-carboxylate hydrochloride | HCID 22827650 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 54405893 | HCID 54405893 | 84% |
Reaction Steps
Using General Procedure A with 2.0 g (8.2 mmol) D-Proline benzyl ester hydrochloride and 800 mg (4.1 mmol) 1,3-phenylenediacetic acid afforded, after flash chromatography (EtOAc), 1.93 g (84%) of the title compound as a colorless oil. MS m/e (%): 586 (M+NH4+, 100), 569 (M+H+, 60).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06262089B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-19b38333243d43fa9a11b0bcb381466f |
| Source note | uspto-grants-2001_07 |