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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1386005Generated: October 31, 2026

Potassium Carbonate → Ethyl 3-[4-[2-(2,3-dihydro-1,4-benzoxazin-4-yl)ethoxy]phenyl]-2-hydroxypropanoate

https://huagongshe.com/reaction/1386005

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant2-(2,3-Dihydro-1,4-benzoxazin-4-yl)ethyl methanesulfonateHCID 10422590—
ReactantEthyl p-hydroxyphenyllactateHCID 21930973—
ProductEthyl 3-[4-[2-(2,3-dihydro-1,4-benzoxazin-4-yl)ethoxy]phenyl]-2-hydroxypropanoateHCID 992934532%

Reaction Steps

The title compound (0.14 g, 32%) was prepared as a gummy liquid from 2-(2,3-dihydro-1,4-benzoxazin-4-yl)ethyl methanesulfonate (0.36 g, 1.42 mmol), potassium carbonate (0.80 g, 5.8 mmol) and ethyl 2-hydroxy-3-(4-hydroxyphenyl)propanoate (0.3 g, 1.42 mmol) using conditions analogous to that described in preparation 2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06265401B1
Source datasetuspto-grants-2001_07
ORD IDord-05002a0b81d24f38964247999cabe044
Source noteuspto-grants-2001_07