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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1386086Generated: November 1, 2026

Acetone → HCID 131722785, compound

https://huagongshe.com/reaction/1386086

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetoneHCID 180—
ReactantSodium IodideHCID 5238—
ReactantSodium CarbonateHCID 10340—
Reactant2,6-Dimethylbenzyl ChlorideHCID 221154—
ReactantEthyl 8-amino-2-methylimidazo[1,2-a]pyridine-3-carboxylateHCID 21717338—
ProductHCID 131722785HCID 131722785—

Reaction Steps

A mixture of 8-amino-3-carboethoxy-2-methylimidazo[1,2-a]pyridine (6.08 g, 27.74 mmol), 2,6-dimethylbenzylchloride (4.5 g, 29.13 mmol), sodium carbonate (4.32 g, 43.7 mmol), sodium iodide (0.7 g) and acetone (120 ml) was stirred for 30 h and the crystalline product was filtered off. The yield was dissolved in dichloromethane filtered and the solvent was evaporated under reduced pressure to give the title product (7.0 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06265415B1
Source datasetuspto-grants-2001_07
ORD IDord-7fa49510ae124196bdc9d8c02d90befa
Source noteuspto-grants-2001_07