HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → HCID 131722785, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 2,6-Dimethylbenzyl Chloride | HCID 221154 | — |
| Reactant | Ethyl 8-amino-2-methylimidazo[1,2-a]pyridine-3-carboxylate | HCID 21717338 | — |
| Product | HCID 131722785 | HCID 131722785 | — |
Reaction Steps
A mixture of 8-amino-3-carboethoxy-2-methylimidazo[1,2-a]pyridine (6.08 g, 27.74 mmol), 2,6-dimethylbenzylchloride (4.5 g, 29.13 mmol), sodium carbonate (4.32 g, 43.7 mmol), sodium iodide (0.7 g) and acetone (120 ml) was stirred for 30 h and the crystalline product was filtered off. The yield was dissolved in dichloromethane filtered and the solvent was evaporated under reduced pressure to give the title product (7.0 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06265415B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-7fa49510ae124196bdc9d8c02d90befa |
| Source note | uspto-grants-2001_07 |