反应详情

A solution of 6-methoxy-3-((pivaloyloxy)methyl)-7-(4-pyridylmethoxy)-3,4-dihydroquinazolin-4-one (500 mg, 1.26 mmol) in saturated methanolic ammonia (10 ml) was stirred for 20 hours at ambient temperature. The volatiles were removed by evaporation, the solid residue was triturated with ether, collected by filtration and dried under vacuum to give 6-methoxy-7-(4-pyridylmethoxy)-3,4-dihydroquinazolin-4-one (330 mg, 92%).

1. customThe volatiles were removed by evaporation
2. customthe solid residue was triturated with ether
3. filtrationcollected by filtration
4. customdried under vacuum