HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1386584Generated: November 2, 2026
p-(Hexyloxy)benzaldehyde → HCID 21182493, compound
https://huagongshe.com/reaction/1386584
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | p-(Hexyloxy)benzaldehyde | HCID 79816 | — |
| Reactant | 3,5-Diamino-2-methylbenzoic acid | HCID 135524 | — |
| Solvent | Nitrobenzene | HCID 7416 | — |
| Product | HCID 21182493 | HCID 21182493 | 48.9% |
Reaction Steps
A mixture of Methyl 3,4-diaminobenzoate (1.84 g) and 4-hexyloxy benzaldehyde (2.30 g) in nitrobenzene (40 ml) was stirred for 48 hours at 145° C. After cooling, the mixture was evaporated under reduced pressure. Purification of the residue by column chromatography on silica gel eluted with (n-hexane:ethyl acetate=2:1) gave 5-Methoxycarbonyl-2-(4-hexyloxyphenyl)benzimidazole (1.91 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06265536B1 |
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| Source dataset | uspto-grants-2001_07 |
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| ORD ID | ord-43a621d41eaf4a6cb2bf2126aca2a486 |
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| Source note | uspto-grants-2001_07 |
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