Hydrochloric Acid → HCID 57094435, compound

Participants

Reaction Steps

The title compound was prepared from 39 mg (0.085 mmol) of 2-(R)-(3-(R)-formyl-4-(S)-phenylpyrrolidin-1-yl)-(2-chlorophenyl)acetic acid, 4-(methoxy)benzyl ester (from EXAMPLE 10, Step D) and 4-(3-phenylpropyl)piperidine.HCl using a procedure analogous to that described in EXAMPLE 1, Step J to provide 38 mg (69%) of the title compound: RF: 0.28 (4:1 v/v hexanes/EtOAc); 1H NMR (300 MHz) δ 1.05-1.23 (m, 5H), 1.47-1.75 (m, 7H), 2.30-2.97 (m, 11H), 4.76 (s, 1H), 5.06 (s, 2H), 6.78-6.83 (m, 2H), 7.13-7.36 (m, 15H), 7.68 (m, 1H).

Provenance & Evidence