Trifluoroacetic acid → HCID 54258983, compound

Participants

Reaction Steps

A solution of 37 mg (0.1 mmol) of 1-t-butoxycarbonyl-4-(3-((4-carbomethoxy)phenyl)propyl)piperidine (from EXAMPLE 29, Step A) in CH2Cl2 at 0° C. was treated with 1.0 mL of TFA. The cooling bath was removed and the solution was stirred at rt for 1 h. The mixture was concentrated. The residue was dissolved in 2×5 mL of ether and concentrated to remove excess TFA. The crude product was used in Step C without further purification.

Provenance & Evidence