HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphonic acid → Glyphosate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphonic acid | HCID 407 | — |
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | 2,5-Piperazinedione | HCID 7817 | — |
| Reactant | HCID 178479783 | HCID 178479783 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | Glyphosate | HCID 3496 | — |
Reaction Steps
The sequence of reactions in Reaction Scheme 9a is comparable to those set forth in Reaction Scheme 9 except that N-acetylglycine XVIII is deacylated to form 2,5-diketopiperazine XXX. 2,5-diketopiperazine XXX is then reacted with formaldehyde and H3PO3 PCl3 or other H3PO3 source to produce N-(phosphonomethyl)glycine I and acetic acid. Acetic acid which is produced in the hydrolysis step can be reacted with ammonia to generate acetamide for the carboxymethylation step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06265605B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-f7bfb1c4a3c64766a103a724f951a1f8 |
| Source note | uspto-grants-2001_07 |