Dimethylamine → HCID 21180326, compound

HRID 1386933Notes

Reaction equation

[F:1][CH:2]([F:24])[N:3]1[C:7]([C:8]2[CH:9]=[C:10]([CH:13]=[CH:14][CH:15]=2)[CH:11]=O)=[N:6][C:5]([C:16]2[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[CH:18][CH:17]=2)=[N:4]1.[CH3:25][NH:26][CH3:27]>>[F:24][CH:2]([F:1])[N:3]1[C:7]([C:8]2[CH:9]=[C:10]([CH:13]=[CH:14][CH:15]=2)[CH2:11][N:26]([CH3:27])[CH3:25])=[N:6][C:5]([C:16]2[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[CH:18][CH:17]=2)=[N:4]1

Participants

Reactant 2

HCID 674Dimethylamine

HCID 21180365HCID 21180365, compound

Product 1

HCID 21180326HCID 21180326, compound

Procedure

Using 3-[2-difluoromethyl-5-(4-methoxy-phenyl)-2H-[1,2,4]triazol-3-yl]-benzaldehyde and dimethylamine the title compound was prepared as a white amorphous solid (83.4% yield), MS: m/e=359.168 (M+H+).

Sources & evidence

ORD record: ord-78b6ddc34d9640688054a678201ab4a5
Source dataset: uspto-grants-2001_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06265426B1

Reaction notes

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