Benzo(B)Thiophene → HCID 21182775, compound

HRID 1386977Notes

Reaction equation

HRID 1386977 reaction equation
[S:1]1[CH:5]=[CH:4][C:3]2[CH:6]=[CH:7][CH:8]=[CH:9][C:2]1=2.[Br:10][C:11]1[CH:12]=[C:13]([CH:17]=[CH:18][C:19]=1[O:20][CH3:21])[C:14]([OH:16])=O>>[Br:10][C:11]1[CH:12]=[C:13]([C:14]([C:4]2[C:3]3[CH:6]=[CH:7][CH:8]=[CH:9][C:2]=3[S:1][C:5]=2[C:13]2[CH:17]=[CH:18][C:19]([O:20][CH3:21])=[CH:11][CH:12]=2)=[O:16])[CH:17]=[CH:18][C:19]=1[O:20][CH3:21]

Participants

3

Reactant 2

HCID 7221Benzo(B)ThiopheneHCID 668363-Bromo-4-methoxybenzoic acid

Product 1

HCID 21182775HCID 21182775, compoundYield 76%

Procedure

The title compound was prepared in 76% yield from 2-(4-methoxyphenyl)]benzo[b]thiophene (Example 3, Part A) and 3-bromo-4-methoxybenzoic acid by essentially following the procedures detailed in Example 2, Part C.

Sources & evidence

ORD record
ord-4f033bb26a7542afa34b09125962db01
Source dataset
uspto-grants-2001_07
Patent number
US06265575B1

Reaction notes

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