HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethylaminoethyl chloride → HCID 18357191, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethylaminoethyl chloride | HCID 13364 | — |
| Reactant | HCID 21182750 | HCID 21182750 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 18357191 | HCID 18357191 | — |
Reaction Steps
By essentially following the procedure outlined in Example 3, part D, the title compound was prepared from 4-hydroxyphenyl 2-(4-methoxyphenyl)benzo[b]thiophen-3-yl ketone (Example 28, Part A) and 2-diethylaminoethyl chloride in 86% yield. Flash chromatography [SiO2; gradient 1-4% of (1:1 TEA-MeOH) in EtOAc] gave the desired compound as a light oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06265575B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-49c6d397e2c44a65bc3936c008c783fc |
| Source note | uspto-grants-2001_07 |