Piperidine, 1-(2-chloroethyl)-, hydrochloride → HCID 9869383, compound

HRID 1387007Notes

Reaction equation

HRID 1387007 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:10]2[C:11]3[CH:26]=[CH:25][CH:24]=[CH:23][C:12]=3[S:13][C:14]=2[C:15]2[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=2)=[O:9])=[CH:4][CH:3]=1.Cl.Cl[CH2:29][CH2:30][N:31]1[CH2:36][CH2:35][CH2:34][CH2:33][CH2:32]1>>[N:31]1([CH2:30][CH2:29][O:1][C:2]2[CH:3]=[CH:4][C:5]([C:8]([C:10]3[C:11]4[CH:26]=[CH:25][CH:24]=[CH:23][C:12]=4[S:13][C:14]=3[C:15]3[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=3)=[O:9])=[CH:6][CH:7]=2)[CH2:36][CH2:35][CH2:34][CH2:33][CH2:32]1

Participants

3

Reactant 2

HCID 74826Piperidine, 1-(2-chloroethyl)-, hydrochlorideHCID 21182750HCID 21182750, compound

Product 1

HCID 9869383HCID 9869383, compoundYield 81%

Procedure

The title compound was prepared using 2-(4-methoxyphenyl)benzo[b]thiophen-3-yl 4-hydroxyphenyl ketone and 1-(2-chloroethyl)piperidine hydrochloride in 81% yield by essentially following the same procedures detailed in Example 24, Part B.

Sources & evidence

ORD record
ord-5f29285aca0348b59446f1d37bf9536f
Source dataset
uspto-grants-2001_07
Patent number
US06265575B1

Reaction notes

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