N-(2-(p-bromophenoxy)ethyl)pyrrolidine → HCID 21182680, compound

HRID 1387026Notes

Reaction equation

HRID 1387026 reaction equation
[CH3:1][O:2][C:3]1[CH:14]=[CH:13][C:6]2[S:7][C:8](B(O)O)=[CH:9][C:5]=2[CH:4]=1.Br[C:16]1[CH:29]=[CH:28][C:19]([O:20][CH2:21][CH2:22][N:23]2[CH2:27][CH2:26][CH2:25][CH2:24]2)=[CH:18][CH:17]=1>>[CH3:1][O:2][C:3]1[CH:14]=[CH:13][C:6]2[S:7][C:8]([C:16]3[CH:17]=[CH:18][C:19]([O:20][CH2:21][CH2:22][N:23]4[CH2:24][CH2:25][CH2:26][CH2:27]4)=[CH:28][CH:29]=3)=[CH:9][C:5]=2[CH:4]=1

Participants

3

Reactant 2

HCID 70657N-(2-(p-bromophenoxy)ethyl)pyrrolidineHCID 21706311(5-Methoxy-1-benzothiophen-2-yl)boronic acid

Product 1

HCID 21182680HCID 21182680, compoundYield 47%

Procedure

The title compound was prepared in 47% yield by essentially following the procedures in Example 1, Part B, from 5-methoxybenzo[b]thiophene-2-boronic acid (Part B) and 1-(2-(4-bromophenoxy)ethyl)pyrrolidine.

Sources & evidence

ORD record
ord-6a5a60c62b374ebab2d13f0757e251d1
Source dataset
uspto-grants-2001_07
Patent number
US06265575B1

Reaction notes

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