HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 138704Generated: October 25, 2026
Hydrochloric Acid → 7-[2-amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-N-(oxolan-3-yl)-3,4-dihydro-1H-isoquinoline-2-carboxamide
https://huagongshe.com/reaction/138704
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | Phosgene | HCID 6371 | — |
| Reactant | Oxolan-3-amine | HCID 3365553 | — |
| Reactant | 4-(4-Methylpiperazin-1-yl)-6-(1,2,3,4-tetrahydroisoquinolin-7-yl)pyrimidin-2-amine | HCID 49779438 | — |
| Product | 7-[2-amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-N-(oxolan-3-yl)-3,4-dihydro-1H-isoquinoline-2-carboxamide | HCID 72307895 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (9/10) |
|---|
| ORD ID | ord-dab0f9eb028148fb86b5ddac2021b86b |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (9/10) |
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