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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1387052Generated: November 1, 2026

N-(4-bromophenyl)-2-(pyrrolidin-1-yl)acetamide → N-[4-(6-Methoxybenzo[b]thiophen-2-yl)phenyl]-alpha-(1-pyrrolidinyl)acetamide

https://huagongshe.com/reaction/1387052

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(4-bromophenyl)-2-(pyrrolidin-1-yl)acetamideHCID 1091709—
Reactant(6-Methoxy-1-benzothiophen-2-yl)boronic acidHCID 10560276—
ProductN-[4-(6-Methoxybenzo[b]thiophen-2-yl)phenyl]-alpha-(1-pyrrolidinyl)acetamideHCID 2118288597%

Reaction Steps

By essentially following the procedures described in Example 1, Part B, the title compound was prepared in 97% yield from N-(4-bromophenyl)-α-(1-pyrrolidinyl)acetamide (Part B) and 6-methoxybenzo[b]thiophene-2-boronic acid (Example 1, Part A).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06265575B1
Source datasetuspto-grants-2001_07
ORD IDord-48d8eba55f2b49bb92d98d802b8a706f
Source noteuspto-grants-2001_07