HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22462661, compound → HCID 21182900, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22462661 | HCID 22462661 | — |
| Reactant | 1-[2-(4-Bromo-2-methoxyphenoxy)ethyl]pyrrolidine | HCID 22994338 | — |
| Product | HCID 21182900 | HCID 21182900 | 30% |
Reaction Steps
The title compound was prepared from 6-benzyloxy-2-(dimethylamino)benzo[b]thiophen-3-yl 3-methyl-4-[(1-pyrrolidinyl)methyl]phenyl ketone (Example 124, Part C) and 4-bromo-2-methoxyphenyl 2-(1-pyrrolidinyl)ethyl ether (Part A) in 30% yield after PrepLC (SiO2; gradient of 80:15:5 to 70:25:5 hexanes-THF-TEA) by essentially following the procedure detailed in Example 123, Part A.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06265575B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-f53948760fad409799ed1f96565d4b75 |
| Source note | uspto-grants-2001_07 |