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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1387118Generated: October 26, 2026

5-Bromo-2-hydroxybenzyl alcohol → 1-[2-(2-Hydroxymethyl-4-bromophenoxy)ethyl]pyrrolidine

https://huagongshe.com/reaction/1387118

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-2-hydroxybenzyl alcoholHCID 75342—
Reactant1-(2-Chloroethyl)pyrrolidine hydrochlorideHCID 81668—
Product1-[2-(2-Hydroxymethyl-4-bromophenoxy)ethyl]pyrrolidineHCID 2118286352%

Reaction Steps

The title compound was prepared in 52% yield by essentially following the procedures outlined in Example 3, Part D, from 1-(2-chloroethyl)pyrrolidine hydrochloride and 5-bromo-2-hydroxybenzyl alcohol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06265575B1
Source datasetuspto-grants-2001_07
ORD IDord-9fa8ce5d6c724ab588127dda64810c7c
Source noteuspto-grants-2001_07