Trifluoromethanesulfonate → HCID 54260639, compound

HRID 1387124Notes

Reaction equation

HRID 1387124 reaction equation
[N:1]1([CH2:6][CH2:7][O:8][C:9]2[CH:14]=[CH:13][C:12]([C:15]3[S:19][C:18]4[CH:20]=[CH:21][CH:22]=[CH:23][C:17]=4[CH:16]=3)=[CH:11][CH:10]=2)[CH2:5][CH2:4][CH2:3][CH2:2]1.[O-:24][S:25]([C:28]([F:31])([F:30])[F:29])(=[O:27])=[O:26]>>[N:1]1([CH2:6][CH2:7][O:8][C:9]2[CH:14]=[CH:13][C:12]([C:15]3[S:19][C:18]4[CH:20]=[CH:21][C:22]([O:27][S:25]([C:28]([F:31])([F:30])[F:29])(=[O:26])=[O:24])=[CH:23][C:17]=4[CH:16]=3)=[CH:11][CH:10]=2)[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 2758875TrifluoromethanesulfonateHCID 106637082-[4-[2-(1-Pyrrolidinyl)ethoxy)phenyl]benzo[b]thiophene

Product 1

HCID 54260639HCID 54260639, compoundYield 56%

Procedure

The title compound was prepared from 5-methoxy-[2-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]benzo[b]thiophene in 56% yield for 2 steps via demethylation previously described and triflate formation by a conventional method.

Sources & evidence

ORD record
ord-1c0d9ecc25bd473ca0be25a035ccebbb
Source dataset
uspto-grants-2001_07
Patent number
US06265575B1

Reaction notes

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