5-Methyl-1,3,4-oxadiazole-2-carboxylic acid → 1-ethyl-3-[4-[4-(3-methylmorpholin-4-yl)-7-(5-methyl-1,3,4-oxadiazole-2-carbonyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea

HRID 138718Notes

Reaction equation

HRID 138718 reaction equation
[CH2:1]([CH3:2])[NH:3][C:4](=[O:5])[NH:6][c:7]1[cH:8][cH:9][c:10](-[c:13]2[n:14][c:15]([N:23]3[CH:24]([CH3:29])[CH2:25][O:26][CH2:27][CH2:28]3)[c:16]3[c:17]([n:18]2)[CH2:19][NH:20][CH2:21][CH2:22]3)[cH:11][cH:12]1.[CH3:30][c:31]1[n:32][n:33][c:34]([C:36](=[O:37])[OH:38])[o:35]1>>[CH2:1]([CH3:2])[NH:3][C:4](=[O:5])[NH:6][c:7]1[cH:8][cH:9][c:10](-[c:13]2[n:14][c:15]([N:23]3[CH:24]([CH3:29])[CH2:25][O:26][CH2:27][CH2:28]3)[c:16]3[c:17]([n:18]2)[CH2:19][N:20]([C:36]([c:34]2[n:33][n:32][c:31]([CH3:30])[o:35]2)=[O:37])[CH2:21][CH2:22]3)[cH:11][cH:12]1

Participants

3

Reactant 2

HCID 198119465-Methyl-1,3,4-oxadiazole-2-carboxylic acidHCID 666875921-Ethyl-3-[4-[4-(3-methylmorpholin-4-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl]phenyl]urea

Product 1

HCID 671810751-ethyl-3-[4-[4-(3-methylmorpholin-4-yl)-7-(5-methyl-1,3,4-oxadiazole-2-carbonyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea

Sources & evidence

ORD record
ord-5e7adafe5d8b4a7e84dda8632b6cbbef
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…