HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1387236Generated: October 31, 2026
2-Amino-5-(trifluoromethyl)pyridine → HCID 18504582, compound
https://huagongshe.com/reaction/1387236
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Amino-5-(trifluoromethyl)pyridine | HCID 735862 | — |
| Reactant | 1-[4-(3,3-Dichloroprop-2-enyloxy)-2,6-dichlorophenoxy]-3-bromopropane | HCID 10884069 | — |
| Product | HCID 18504582 | HCID 18504582 | 12% |
Reaction Steps
A mixture of 1.0 g of 1-(3-bromopropyloxy)-2,6-dichloro-4-(3,3-dichloro-2-propenyloxy)benzene and 4.0 g of 2-amino-5-(trifluoromethyl)pyridine was stirred at 90° C. for 3 hours. The reaction mixture was cooled to room temperature, and subjected to silica gel chromatography, which afforded 0.14 g of 3,5-dichloro-1-(3,3-dichloro-2-propenyloxy)-4-(3-(5-(trifluoromethyl)-2-pyridylamino)propyloxy)benzene (12% yield), nD25.0 1.5525.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06268313B1 |
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| Source dataset | uspto-grants-2001_07 |
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| ORD ID | ord-31ce57a72f2b47eca58e2e48c209e3f7 |
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| Source note | uspto-grants-2001_07 |
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