5-Ethynyl-4-methyl-3-nitro-2-pyridone → 3-Amino-5-ethyl-4-methyl-2-pyridone

Beteiligte Stoffe

Reaktionsschritte

A mixture of 5-ethynyl-4-methyl-3-nitro-2-pyridone (0.18 g, 0.6 mmol) and 10% Pd/C (0.02 g) in ethanol/ethyl acetate (50 mL, 1/1) was hydrogenated at 35 psi in a Parr apparatus overnight. The catalyst was removed by filtration, and the solvents were evaporated to give 3-amino-5-ethyl-4-methyl-2-pyridone.

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