참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Iodine | HCID 807 | — |
| 반응물 | Water | HCID 962 | — |
| 반응물 | 2-Hydroxy-4-methyl-3-nitropyridine | HCID 345370 | — |
| 반응물 | Sodium Iodate | HCID 23675764 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 용매 | Sulfuric Acid | HCID 1118 | — |
| 생성물 | 5-Iodo-4-methyl-3-nitro-1,2-dihydropyridin-2-one | HCID 21706514 | — |
반응 단계
To a solution of 4-methyl-3-nitro-2-pyridone (2.00 g, 13 mmol) in acetic acid (12 mL) and concentrated sulfuric acid (1.6 ml,) was added iodine (1.32 g) and sodium iodate (0.55 g). The mixture was heated at 75° C. for 2.5 hours and then stirred at rt overnight. Water (100 mL) was added, and the precipitated 5-iodo-4-methyl-3-nitro-2-pyridone was collected by filtration (2.97 g, 82%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06268365B1 |
|---|
| 출처 데이터셋 | uspto-grants-2001_07 |
|---|
| ORD ID | ord-4e8af721267749e8b617049bd221cc3a |
|---|
| 출처 메모 | uspto-grants-2001_07 |
|---|
