HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Hexyl-4-methyl-3-nitro-5-methoxycarbonyl-2-pyridone → 3-Amino-1-hexyl-4-methyl-5-methoxycarbonyl-2-pyridone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Hexyl-4-methyl-3-nitro-5-methoxycarbonyl-2-pyridone | HCID 21706505 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 3-Amino-1-hexyl-4-methyl-5-methoxycarbonyl-2-pyridone | HCID 21706534 | 101.9% |
Reaction Steps
A mixture of 1-hexyl-4-methyl-3-nitro-5-methoxycarbonyl-2-pyridone (0.145 g, 0.49 mmol) and a catalytic amount of 10% Pd/C in ethyl acetate (100 mL) was hydrogenated at 45 psi in a Parr apparatus for 5 hours. The catalyst was removed by filtration and the solvent was evaporated to give 3-amino-1-hexyl-4-methyl-5-methoxycarbonyl-2-pyridone (0.133 g, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06268365B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-428d4e590fca4395ae3b97f8a5835bc2 |
| Source note | uspto-grants-2001_07 |