HCID 21706541, compound → HCID 21706524, compound

Participants

Reaction Steps

A mixture of 4-benzyloxycarbonylamino-2-(4-methoxybenzyl)-5-methyl-3 -pyridazinone (0.39 g, 1.0 mmol) and 10% Pd/C (0.10 g) in ethanol (40 mL) and ethyl acetate (5 mL) was hydrogenated at 45 psi in a Parr apparatus for 1.3 hours. The catalyst was removed by filtration and the solvents were evaporated to give 4-amino-2-(4-methoxybenzyl)-5-methyl-3-pyridazinone (0.23 g, 1.0 mmol 910%).

Provenance & Evidence