N,N,2-trimethyl-3-nitroaniline → 1,3-Benzenediamine,N,N,2-trimethyl-(9CI)
Reaction equation
[CH3:1][N:2]([CH3:13])[C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([N+:9]([O-])=O)[C:4]=1[CH3:12]>CO.[H][H].[Ni]>[CH3:1][N:2]([CH3:13])[C:3]1[C:4]([CH3:12])=[C:5]([CH:6]=[CH:7][CH:8]=1)[NH2:9]Participants
5
Reactant 1
Product 1
Reagents, catalysts & solvents 3
Procedure
73 g of N,N-dimethyl-2-methyl-3-nitroaniline are dissolved in 800 ml of methanol and hydrogenated at 20° C under 5 bar of hydrogen using Raney nickel as catalyst. 57 g of 3-dimethylamino-2-methylaniline are obtained.
Sources & evidence
- ORD record
- ord-8d64135455624c5680fa839f892dd309
- Source dataset
- uspto-grants-2001_07
- Patent number
- US06268389B1
Reaction notes
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