反应详情

A mixture of 4-3 (460 mg, 1.0 mmol) and 10% Pd/carbon (300 mg) in EtOH (20 mL) was stirred under a balloon of hydrogen for 3 h. Following filtration and evaporative removal of the solvent, the residue was chromatographed (silica gel, 70:25:5 chloroform/ethyl acetate/MeOH) to give 4-4 as a yellow oil.

1. filtrationfiltration
2. customremoval of the solvent
3. customthe residue was chromatographed (silica gel, 70:25:5 chloroform/ethyl acetate/MeOH)