HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Ethyl-2-((2-Hydroxymethylphenyl)thiomethyl)hexenal → 2-Ethyl-2-((2-formylphenyl)thiomethyl)hexenal
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Ethyl-2-((2-Hydroxymethylphenyl)thiomethyl)hexenal | HCID 54430931 | — |
| Reactant | HCID 178418287 | HCID 178418287 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-Ethyl-2-((2-formylphenyl)thiomethyl)hexenal | HCID 53756105 | 66% |
Reaction Steps
A mixture of 3.7 g of 16, 5.6 g (0.026 mole) of pyridinium chlorochromate, 2 g of Celite and 30 mL of methylene chloride was stirred for 18 h and filtered through a bed of silica gel. The silica gel was eluted with methylene chloride. The combined methylene chloride eluant was purified by HPLC (20% ETOAc-hexane) to give 2.4 g (66%) of an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06268392B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-da32502e66124c60bf2b27ac1b3314e4 |
| Source note | uspto-grants-2001_07 |