HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloroaniline → 3-Amino-4-methoxy-N-(4-chlorophenyl)-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloroaniline | HCID 7812 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 4-Methoxy-3-nitrobenzoic acid | HCID 66640 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Product | 3-Amino-4-methoxy-N-(4-chlorophenyl)-benzamide | HCID 16792992 | 27.7% |
Reaction Steps
Prepared according to the procedure described for Example 1 using oxalyl chloride (5.5 mL, 63.05 mmol), 4-methoxy-3-nitrobenzoic acid (11.30 g, 57.32 mmol), dimethylformamide (1.0 mL, 1.29 mmol), and 4-chloroaniline (14.6 g, 114 mmol) to afford the product (4.4 g); m.p. 191-192° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06268387B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-743a917fafc841fe83db3031a8d18b9a |
| Source note | uspto-grants-2001_07 |