HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 3-Amino-4-methoxy-N-(3,4-dimethylphenyl)-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 3,4-Dimethylaniline | HCID 7248 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 4-Methoxy-3-nitrobenzoic acid | HCID 66640 | — |
| Product | 3-Amino-4-methoxy-N-(3,4-dimethylphenyl)-benzamide | HCID 16786027 | 87.4% |
Reaction Steps
Prepared according to the procedure described for Example 1 using oxalyl chloride (3.0 mL, 34.4 mmol), 4-methoxy-3-nitrobenzoic acid (5.00 g, 25.36 mmol), dimethylformamide (1.0 mL, 12.92 mmol), and 3,4-dimethylaniline (6.2 g, 51 mmol) to afford the product (5.99 g), m.p. 138-142° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06268387B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-85a0de1b345744d5908a1bc7c24f321c |
| Source note | uspto-grants-2001_07 |